PhD Researcher · Cancer Biology

Decoding the hidden
language of cancer cells.

I'm a biomedical sciences PhD researcher at Swansea University, working at the intersection of tumour microenvironment biology and liquid-biopsy diagnostics — and building open tools so other researchers can build on the work.

3+
Years researching
8+
Publications
50+
Open protocols
Researcher in a biomedical laboratory

Deniz Akin

Biomedical Sciences · PhD Candidate

Swansea University
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Tumour microenvironmentLiquid biopsySpatial transcriptomicsDrug discoverySingle-cell genomicsImmune profilingOpen scienceTranslational oncologyTumour microenvironmentLiquid biopsySpatial transcriptomicsDrug discoverySingle-cell genomicsImmune profilingOpen scienceTranslational oncologyTumour microenvironmentLiquid biopsySpatial transcriptomicsDrug discoverySingle-cell genomicsImmune profilingOpen scienceTranslational oncology
What I work on

Three threads, one question: why does cancer behave the way it does?

My PhD weaves together complementary perspectives — from molecular detection through to therapeutic resistance — to make cancer care more precise and more humane.

Cellular & Spatial Biology

How cells organise within a tumour — and what their neighbourhoods reveal about disease progression and treatment response.

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Molecular Diagnostics

Building liquid-biopsy assays that detect cancer earlier, by combining cell-free DNA, EV proteomics and machine-learning classifiers.

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Translational Therapeutics

Identifying actionable vulnerabilities through high-throughput screening, validated in patient-derived organoids and in vivo models.

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Current work

Selected research

All projects
Mapping the Tumour Microenvironment in Triple-Negative Breast Cancer
Ongoing

Molecular Oncology · 2024–2026

Mapping the Tumour Microenvironment in Triple-Negative Breast Cancer

Investigating how stromal cells and immune infiltrates shape disease progression in TNBC using spatial transcriptomics and multiplexed imaging across patient-derived tissue cohorts.

Spatial transcriptomics10x Visium / CODEX imaging
Circulating Biomarkers for Early Detection of Pancreatic Cancer
Ongoing

Biomarker Discovery · 2023–2025

Circulating Biomarkers for Early Detection of Pancreatic Cancer

Developing a multi-analyte liquid biopsy panel combining cell-free DNA methylation signatures with extracellular vesicle proteomics to detect pancreatic adenocarcinoma at resectable stages.

cfDNA methylationEV proteomics
Targeted Kinase Inhibitor Screen for Resistant Glioblastoma
Completed

Therapeutics · 2023–2024

Targeted Kinase Inhibitor Screen for Resistant Glioblastoma

A high-throughput screen of clinically advanced kinase inhibitors against patient-derived glioblastoma stem cells, identifying synergistic combinations that overcome temozolomide resistance.

High-throughput screening3D spheroid models
By the numbers

A quiet, persistent body of work.

0+

Years of research

0+

Research projects

0+

Peer-reviewed papers

0+

Open lab protocols

Cancer research moves forward in increments — but the cumulative effect is enormous. My work is to add honest, reproducible increments, and to share them openly so others can build on them.

Research philosophy

Collaborate

If your research touches mine,
let's talk.

I'm always open to collaborations with other researchers, clinicians, and groups working in cancer biology or open bioinformatics tooling.

Now hiring perspectives

  • Clinical oncology collaborators (TNBC, HCC, PDAC)
  • Computational biologists for spatial / single-cell
  • PhD candidates interested in joint methods work
  • Open-source contributors for BioOps protocols